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  • Title: [Heart preservation by means of hypothermia and hyperbaric oxygenation].
    Author: Usvatova IIa, Stupin IV, Petukhov EB, Musin II, Istomin NP.
    Journal: Kardiologiia; 1976 Jan; 16(1):124-7. PubMed ID: 1271613.
    Abstract:
    The efficiency of the methods of hypothermia and hyperbaric oxygenation for the preservation of canine hearts was studied. The cardiac function was found to reestablish itself nearly completely after 3 hours of preservation, despite some significant metabolic shifts -- disintegration of oxidation and phosphorylation, activation of lysosomal enzymes, reduction of the store of adenyl macroergs and biogenic amines. Five hours of preservation result in irreversible changes in the heart.
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