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  • Title: Korean medicinal plants inhibiting to human immunodeficiency virus type 1 (HIV-1) fusion.
    Author: Chang YS, Woo ER.
    Journal: Phytother Res; 2003 Apr; 17(4):426-9. PubMed ID: 12722157.
    Abstract:
    In order to find novel anti-HIV agents from natural products, 80 MeOH extracts of Korean plants were applied to a syncytia formation inhibition assay, which is based on the interaction between the HIV-1 envelope glycoprotein gp120/41 and the cellular membrane protein CD4 of T lymphocytes. The most potent HIV-1 fusion inhibition was shown by the stem bark of Ailanthus altissima with 74.9 +/- 4.4% at a concentration of 100 microg/mL.
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