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  • Title: [Case report of pulmonary epithelioid hemangioendothelioma].
    Author: Hanada N, Namai S, Kobayashi C, Igawa S, Ozawa T, Kobayashi H, Yanase N, Abe T, Takada N, Katagiri M.
    Journal: Nihon Kokyuki Gakkai Zasshi; 2003 Feb; 41(2):144-9. PubMed ID: 12722336.
    Abstract:
    A 45-year-old man was admitted to our hospital because of multiple nodular shadows in the right upper field of a chest radiogram taken at a regular medical checkup. He underwent open lung biopsy. The lung tumor found was diagnosed histologically as pulmonary epithelioid hemangioendothelioma. The tumor cells showed positive staining for CD34 and factor VIII-related antigen. Pulmonary epithelioid hemangioendothelioma (PEH) is a rare lung tumor, of which only 40 cases, including the present case, were reported between 1983 and 2002 in Japan. PEH is a progressive, low-grade malignant tumor that originates from hemangioendothelial cells. In chest radiography or CT scanning, PEH is usually discovered incidentally as multiple nodular shadows. Many cases of PEH are diagnosed by open lung biopsy or thoracoscopic biopsy. No standard therapy for PEH has yet been established, other than resection of a solitary lesion. The present patient has been followed without treatment for five-and-a-half years, and is still alive with no symptoms.
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