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  • Title: Total thyroidectomy and parathyroid autotransplantation for radiation-associated thyroid cancer.
    Author: Paloyan E, Lawrence AM, Brooks MH, Picleman JR.
    Journal: Surgery; 1976 Jul; 80(1):70-6. PubMed ID: 1273769.
    Abstract:
    In seventy patients with nodular thyroids and a history of radiation exposure, total thyroidectomy disclosed a 54% incidence of carcinoma; more than half of them had cervial node metastases; four had distant metastases. Fourteen patients required radical neck dissection. The carcinoma was multicentric (both lobes) in 45%. In four patients the carcinoma was found in the lobe contralateral to the one containing the palpable nodule. These findings support the advocates of total thyroidectomy for patients with a nodular thyroid and a history of radiation exposure, provided this operation can be performed with a low incidence of recurrent nerve palsy and hypoparathyroidism.
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