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  • Title: Successful renal transplantation in a child with ANCA-associated microscopic polyangiitis.
    Author: Besbas N, Ozaltin F, Tinaztepe K, Güçer S, Ozen S, Bakkaloglu M, Bakkaloglu A.
    Journal: Pediatr Nephrol; 2003 Jul; 18(7):696-9. PubMed ID: 12743792.
    Abstract:
    Crescentic glomerulonephritis (CGN) is a clinicopathologic entity which is characterized by severe renal dysfunction of rapid onset with glomerular crescents. Type III CGN is associated with the absence of glomerular immune complex deposition (pauci-immune) and is associated with antineutrophil cytoplasmic antibody (ANCA). Microscopic polyangiitis and idiopathic pauci-immune necrotizing glomerulonephritis (NCGN) are strongly associated with ANCA directed against myeloperoxidase (anti-MPO). We describe here an unusual pediatric patient with MPO-ANCA-associated rapidly progressive glomerulonephritis (RPGN), emphasizing the management and outcome of the disease.
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