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  • Title: [The role of the pallidum in regulating cortical activity].
    Author: Sarkisian ZhS, Kazarian LG, Garibian AA, Gambarian LS.
    Journal: Zh Vyssh Nerv Deiat Im I P Pavlova; 1976; 26(2):325-32. PubMed ID: 1274464.
    Abstract:
    Bilateral ablation of the pallidum halves the duration of extinction of conditioned motor food reflexes and contributes to 30 to 50% extinction of the electro-defensive reflexes. Pallidum functional depression by potassium chloride or novacaine leads to a temporary total depression of conditioned motor food reflexes. Depending on the frequency of pallidum stimulation, synchronization or desynchronization of the cortical bioelectrical activity is observed. Ablation of the pallidum in anaesthetized cats results in a high amplitude and low-frequency cortical activity. Injection of large doses of potassium chloride into the pallidum results in a forced running forward which lasts 30 to 40 min. The pallidum is considreed as a structure controlling the cortex activity, which takes part in the mechanisms of sensory information processes in the course of adaptive behaviour.
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