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  • Title: [The effect of ablation of the caudate nucleus on the alimentary zone of the lateral hypothalamus].
    Author: Litvinova AN, Lukhanina EP.
    Journal: Zh Vyssh Nerv Deiat Im I P Pavlova; 1976; 26(2):343-8. PubMed ID: 1274466.
    Abstract:
    A conditioned food-procuring reaction previously elaborated to an acoustic stimulus was reproduced in chronic experiments on six cats by means of direct electrical stimulation of the posterior parts of the lateral hypothalamus. Folloiwng extensive bilateral electrolytic ablation of the caudate nucleus, conditioned food-procuring reaction to the stimulation of the hypothalamus could not be reproduced for 40 to 70 days. The conditioned foor-procuring reflex to the acoustic stimulus disappeared for 14 to 30 days to be subsequently spontaneously restored. After caudatotomy, a diminution of the average amplitude of background oscillations and of evoked potentials to acoustic stimuli was recorced in the examined zones of the lateral hypothalamus. The part played by the caudate nucleus in the processes of alimentary behaviour activation is discussed.
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