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  • Title: Prolonged perilesional edema after treatment of parenchymal neurocysticercosis: methotrexate as a corticosteroid-sparing agent.
    Author: Keiser PB, Nash TE.
    Journal: Clin Infect Dis; 2003 May 15; 36(10):e122-6. PubMed ID: 12746791.
    Abstract:
    Treatment of neurocysticercosis with larvicidal agents is commonly complicated by seizures and transient neurologic deficits as a result of the host immune response to dying cysts. We report a case in which treatment with high-dose praziquantel resulted in prolonged perilesional edema requiring use of corticosteroids and corticosteroid-sparing agents for >1 year, suggesting a role for methotrexate in the management of this condition.
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