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  • Title: Successful treatment of recurrent, intractable hyperemesis gravidarum with methylprednisolone. A case report.
    Author: Chan LY, Lam MH, Lau TK, Chin RK.
    Journal: J Reprod Med; 2003 Apr; 48(4):293-5. PubMed ID: 12746996.
    Abstract:
    BACKGROUND: Severe and persistent hyperemesis gravidarum is a disabling condition. Women may request termination of pregnancy because of the intolerable symptoms and stress. CASE: A woman requested termination of pregnancy because of severe hyperemesis gravidarum. Her first three pregnancies were also complicated by severe and persistent vomiting. The vomiting was successfully treated with a short course of methylprednisolone. CONCLUSION: Methylprednisolone is an effective treatment for severe hyperemesis gravidarum and should be considered for women whose vomiting is persistent and refractory to conventional therapy.
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