These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Unusual number and genomic organization of Hox genes in the tunicate Ciona intestinalis.
    Author: Spagnuolo A, Ristoratore F, Di Gregorio A, Aniello F, Branno M, Di Lauro R.
    Journal: Gene; 2003 May 08; 309(2):71-9. PubMed ID: 12758123.
    Abstract:
    Hox genes are organized in genomic clusters. In all organisms where their role has been studied, Hox genes determine developmental fate along the antero-posterior axis. Hence, these genes represent an ideal system for the understanding of relationships between the number and expression of genes and body organization. We report in this paper that the ascidian Ciona intestinalis genome appears to contain a single Hox gene complex which shows absence of some of the members found in all chordates investigated up to now. Furthermore, the complex appears to be either unusually long or split in different subunits. We speculate that such an arrangement of Hox genes does not correspond to the chordate primordial cluster but occurred independently in the ascidian lineage.
    [Abstract] [Full Text] [Related] [New Search]