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  • Title: Pachyclavulariolides M-R, six novel diterpenoids from a Taiwanese soft coral Pachyclavularia violacea.
    Author: Sheu JH, Wang GH, Duh CY, Soong K.
    Journal: J Nat Prod; 2003 May; 66(5):662-6. PubMed ID: 12762802.
    Abstract:
    Six novel diterpenoids, pachyclavulariolides M-R (1-6), have been isolated from a Taiwanese soft coral Pachyclavularia violacea. The structures and relative stereochemistry of compounds 1-6 were established by spectroscopic analyses. Compound 1 has been shown to exhibit significant cytotoxicity toward P-388 cancer cells. Biosynthesis of 4-6 is discussed.
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