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Title: Terminoside A, a new triterpene glycoside from the bark of Terminalia arjuna inhibits nitric oxide production in murine macrophages. Author: Ali A, Kaur G, Hamid H, Abdullah T, Ali M, Niwa M, Alam MS. Journal: J Asian Nat Prod Res; 2003 Jun; 5(2):137-42. PubMed ID: 12765198. Abstract: Terminoside A (1), a new oleanane-type triterpene was isolated from the acetone fraction of the ethanolic extract of stem bark of Terminalia arjuna. The structure was established as olean-1alpha,3beta,22beta-triol-12-en-28-oic acid-3beta-D-glucopyranoside. On the basis of spectral data and chemical reactions, terminoside A, potently inhibited nitric oxide (NO) production and decreased inducible nitric oxide synthase (iNOS) levels in lipopolysaccharide-stimulated macrophages.[Abstract] [Full Text] [Related] [New Search]