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  • Title: [Treatment of cancer of the nasal cavity in 128 cases].
    Author: Wang K, Shang J, Xu Y.
    Journal: Zhonghua Er Bi Yan Hou Ke Za Zhi; 2000 Jun; 35(3):168-71. PubMed ID: 12768768.
    Abstract:
    OBJECTIVE: To investigate the credibility of combined radiotherapy and surgery for cancer of the nasal cavity and their prognostic factors. METHODS: One hundred and twenty-eight patients were treated from Mar. 1977 to Aug. 1993 receiving either radiotherapy alone (R group, 89), radiotherapy plus surgery (R + S group, 21), surgery plus radiotherapy (S + R group, 13), or surgery alone (S group, 5). RESULTS: The overall 5-year survival rate was 42.2%. The 5-year survival rates of R, R + S and S + R groups were 33.7%, 57.1% and 61.5%, respectively. The 5-year survival rate of combined therapy for squamous cell carcinoma and low differentiated cancer were higher than that of radiotherapy alone, and the effect of radiotherapy alone for undifferentiated carcinoma was better. In early stage, the 5-year survival rate of the radiotherapy alone and combined therapy did not differ significantly. For III and IV stages, the 5-year survival rate of R + S combined therapy was higher than those with radiotherapy alone (P < 0.01). CONCLUSIONS: For early lesions(Stage I and II), R alone or R + S give better results. For advanced lesions(Stage III and IV), combined radiotherapy and surgery is preferred. Radiotherapy alone is indicated for poorly differentiated cancers. Combined radiotherapy plus surgery is preferred for squamous cell carcinoma.
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