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  • Title: Two toxic indole alkaloids from Penicillium islandicum.
    Author: Cole RJ, Kirksey JW, Cutler HG, Wilson DM, Morgan-Jones G.
    Journal: Can J Microbiol; 1976 May; 22(5):741-4. PubMed ID: 1276998.
    Abstract:
    Two new isomeric metabolites, toxins A and B, were isolated from culture extracts of Penicillium islandicum. Both toxins had a molecular formula of C16H15O2N2Cl, and physical and chemical analyses indicated that they were indole alkaloids. LD50 of toxin A was about 75-125 mg/kg in day-old cockerels. Insufficient toxin B was available to determine accurate LD50 values. Toxin A moderately inhibited growth of wheat coleoptiles but did not inhibit growth of week-old intact corn and bean plants. Toxin B showed no plant-growth inhibition.
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