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  • Title: Microbial hydroxylation of progesterone with Acremonium strictum.
    Author: Faramarzi MA, Tabatabaei Yazdi M, Amini M, Zarrini G, Shafiee A.
    Journal: FEMS Microbiol Lett; 2003 May 28; 222(2):183-6. PubMed ID: 12770705.
    Abstract:
    Microbial hydroxylation of progesterone occurred in the culture of Acremonium strictum PTCC 5282 to produce two hydroxylated pregnene-like steroids. The metabolites were purified and characterized using spectroscopic methods and identified as 15alpha-hydroxyprogesterone and 15alpha-hydroxydeoxycorticosterone.
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