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  • Title: Modified noble plication for the prevention of intestinal intussusception after renal transplantation in dogs.
    Author: Kyles AE, Gregory CR, Griffey SM, Bernsteen L, Morris RE.
    Journal: J Invest Surg; 2003; 16(3):161-6. PubMed ID: 12775432.
    Abstract:
    Intestinal intussusception is a frequent problem after experimental transplantation in dogs. This report describes the safety and efficacy of performing a modified Noble plication for the prevention of intussusception. Heterotopic renal transplantation and plication was performed in 20 dogs. Dogs were killed when the serum creatinine concentration exceeded 7 mg/dL because of acute rejection (19 dogs) or venous occlusion (1 dog). Gastrointestinal signs were commonly observed, but no dog experienced an intestinal intussusception, compared to 3 of 14 dogs (21%) previously treated using a similar immunosuppressive regimen. This study supports the routine use of enteroplication in dogs undergoing renal transplantation.
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