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  • Title: [Studies on the arbutin biosynthesis by hairy root of Panax ginseng C.A. Mayer].
    Author: Zhao MQ, Ding JY, Liu J, Hu B.
    Journal: Zhongguo Zhong Yao Za Zhi; 2001 Dec; 26(12):819-22. PubMed ID: 12776328.
    Abstract:
    OBJECTIVE: To study basic conditions for biosynthesis arbutin by the hairy root of Panax ginseng. METHOD: Based on the content of arbutin and the biotransformation rate of hydroquione, these conditions such as the culture stage, the lasting time and the concentration of hydroquione fitting for biosynthesis were found. RESULT: After cultured for 22 days, transferred in fresh B5 medium having 2 mmol.L-1 hydroquione, the hairy root biotransformated hydroquione into arbutin in 24 hours, the bioconversion rate was 89.0% and the content of arbutin in dry root was 13.0%. CONCLUSION: Arbutin, was which never found in the genus of Panax ginseng, can be biosynthesized by the hairy root of Panax ginseng.
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