These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [The protective effects of tea catechins on the injury of cerebral ischemia and reperfusion in rats].
    Author: Fang F, Han YJ, Cui ZQ.
    Journal: Zhongguo Zhong Yao Za Zhi; 2001 Nov; 26(11):777-80. PubMed ID: 12776353.
    Abstract:
    OBJECT: The protective effects of tea catechins on the injury of cerebral ischemia and reperfusion in rats were observed with rat cerebral ischemia and reperfusion model produced by bilaterally clamping the common carotid arteries and vagus nerves for 60 min and then removing the occlusion for 30 min. METHOD: Wistar rats were divided into normal control group, model group and catechin group (30 mg.kg-1 and 50 mg.kg-1 i.p., qd x 7 d). The changes of biochemical indications and pathology were observed. RESULT: The results presented that the concentration of MDA in brain tissue and serum of model rats were higher than that of control rats(P < 0.01). Compared with model group, tea catechin groups could decrease the concentration of MDA in brain tissue and serum, and tea catechin group (50 mg.kg-1 i.p., qd x 7 d) could improve the injury of blood brain barrier. CONCLUSION: Tea catechins have protective effects on the injury of cerebral ischemia and reperfusion in rats.
    [Abstract] [Full Text] [Related] [New Search]