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  • Title: [Vasopressin concentration in the blood and sensitivity of the cardiovascular system to it during aging].
    Author: Frol'kis VV, Golovchenko SF, Pugach BV.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1976 Apr; 62(4):586-93. PubMed ID: 1278535.
    Abstract:
    With aging the content of the blood vasopressin increases. In old animals smaller doses of vasopressin induce coronary insufficiency (rise of T wave, shift of S-T segment, disorders of the atrio-ventricular conductivity). On continuous administration of vasopressin (during a month), arterial hypertension appears only in old animals due to increase in cardiac output, stroke volume at unchanged cardiac rhythm, and to some decrease in the total peripheral resistance.
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