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  • Title: Squamous cell carcinoma developing in a 12-year-old boy with nonHallopeau-Siemens recessive dystrophic epidermolysis bullosa.
    Author: Kawasaki H, Sawamura D, Iwao F, Kikuchi T, Nakamura H, Okubo S, Matsumura T, Shimizu H.
    Journal: Br J Dermatol; 2003 May; 148(5):1047-50. PubMed ID: 12786841.
    Abstract:
    We report a 12-year-old boy with nonHallopeau-Siemens recessive dystrophic epidermolysis bullosa (nHS-RDEB) who developed two skin lesions of squamous cell carcinoma (SCC) on the left foot. The incidence of SCC in nHS-RDEB is much lower than in the HS-RDEB subtype. Furthermore, this boy is the youngest among 92 previously described patients with DEB to develop SCC. This study emphasizes the importance of vigilance in monitoring the possible development of SCC in DEB patients regardless of age or clinical severity.
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