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Title: Parallel approach to selective catalysts for palladium-catalyzed desymmetrization of 2,4-cyclopentenediol. Author: Agarkov A, Uffman EW, Gilbertson SR. Journal: Org Lett; 2003 Jun 12; 5(12):2091-4. PubMed ID: 12790536. Abstract: [reaction: see text] Work toward the development of a bis-phosphine ligand system for the palladium-catalyzed desymmetrization of meso-diols is reported. A parallel approach using phosphine-containing amino acids and a "representational search" was taken to find a polymer-supported catalyst system. The selectivities reported are comparable to many other polymer-bound asymmetric catalysts.[Abstract] [Full Text] [Related] [New Search]