These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Fusion of cells by flipped SNAREs.
    Author: Hu C, Ahmed M, Melia TJ, Söllner TH, Mayer T, Rothman JE.
    Journal: Science; 2003 Jun 13; 300(5626):1745-9. PubMed ID: 12805548.
    Abstract:
    The SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) hypothesis suggests that pairs of proteins known as vesicle (v-) SNAREs and target membrane (t-) SNAREs interact specifically to control and mediate intracellular membrane fusion events. Here, cells expressing the interacting domains of v- and t-SNAREs on the cell surface were found to fuse spontaneously, demonstrating that SNAREs are sufficient to fuse biological membranes.
    [Abstract] [Full Text] [Related] [New Search]