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  • Title: Teflon-induced granuloma: a false-positive finding with PET resolved with combined PET and CT.
    Author: Yeretsian RA, Blodgett TM, Branstetter BF, Roberts MM, Meltzer CC.
    Journal: AJNR Am J Neuroradiol; 2003; 24(6):1164-6. PubMed ID: 12812947.
    Abstract:
    Patients who have undergone thyroidectomy may have recurrent laryngeal nerve injury; until recently, Teflon injection was commonly used for vocal cord medialization. We present a case of a patient who underwent thyroidectomy who had significantly increased and unilateral (18)F-fluorodeoxyglucose uptake in the neck, which was found to be localized to the left vocal cord by use of combined positron emission tomography (PET) and CT, presumably because of a Teflon-induced granuloma. Knowledge of this potential source of false-positive PET interpretation because of its inability to precisely localize neoplastic lesions, and the use of combined PET and CT imaging, may allow precise diagnosis and prevention of unnecessary interventions.
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