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  • Title: [The effect of the bronchoalveolar fluid of mice infected with the influenza virus on hematopoietic bone marrow precursors].
    Author: Lavrov VF, Orlova NG, Dvoretskiĭ AA, Kirilicheva GB, Mamontova TV, Ratgauz GL, Semenkov VF, Ageeva ON.
    Journal: Zh Mikrobiol Epidemiol Immunobiol; 1992; (7-8):45-8. PubMed ID: 1281596.
    Abstract:
    The influence of bronchoalveolar washing fluid (BAWF), as well as BAWF cells, obtained from mice infected with influenza virus, on the formation of exogenic spleen colony-forming units (CFUs) of lethally irradiated syngeneic recipients was studied. BAWF and BAWF cells of intact syngeneic mice stimulated the growth of CFUs. BAWF of mice infected with nonpathogenic strain A/PR/8/34 lost its capacity for stimulating the growth of colonies, and BAWF cells greatly suppressed colony formation in the spleen of recipients. The participation of interferon, colony-stimulating factor and the virus itself in the process of the modulation of colony formation is discussed.
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