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  • Title: A degenerative lesion of the approach to the atrioventricular node producing second-degree and third-degree atrioventricular block.
    Author: Kawai S, Fu L, Aziki K, Okada R, Katoh K.
    Journal: Pacing Clin Electrophysiol; 1992 Dec; 15(12):2263-9. PubMed ID: 1282248.
    Abstract:
    We report a case of a degenerative approach lesion in an 83-year-old male with diabetes mellitus, hypertension, and ischemic heart disease. His ECGs changed from first-degree atrioventricular (AV) block 14 years ago, to third-degree AV (A-H) block. A pacemaker was implanted for bradycardia. He died 4 years later from heart and renal failure. Serial sections through the conduction system revealed total depletion and fatty replacement of the atrial muscle at the approaches to the AV node.
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