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  • Title: The KRAB domain of zinc finger gene ZNF268: a potential transcriptional repressor.
    Author: Sun Y, Gou DM, Liu H, Peng X, Li WX.
    Journal: IUBMB Life; 2003 Mar; 55(3):127-31. PubMed ID: 12822888.
    Abstract:
    Nearly one-third of Krupple-type C2H2 zinc finger proteins have a krupple-associated box (KRAB) domain, which may act as a transcriptional repressor. ZNF268, which was novelty isolated from early human embryo, is a typical krupple-type C2H2 zinc finger protein with a conserved KRAB domain. In this report, the KRAB domain of ZNF268 is identified to localize in the nucleus and has transcriptional repressor activity.
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