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  • Title: CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation.
    Author: Noelle RJ, Ledbetter JA, Aruffo A.
    Journal: Immunol Today; 1992 Nov; 13(11):431-3. PubMed ID: 1282319.
    Abstract:
    The discovery of CD40 and its ligand, gp39, have created new perspectives on the activation of resting B cells by TH cells. Here, Randolph Noelle, Jeffrey Ledbetter and Alejandro Aruffo describe how these molecules were characterized and, from recent findings, examine their relevance to immune activation.
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