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Title: Synthesis and antibacterial activity of oxazolidinone containing sulphonyl group. Author: Cui Y, Yang Y, Chen K, Ji R, Zhang S. Journal: Bioorg Med Chem Lett; 2003 Jul 21; 13(14):2311-3. PubMed ID: 12824024. Abstract: A series of oxazolidinone derivatives carrying sulphonyl group was synthesized and their antibacterial activity was evaluated in vitro. Many of such compounds demonstrated potent antibacterial activity. The activity of a novel compound (YC-20) was 2-4-fold more potent than that of linezolid.[Abstract] [Full Text] [Related] [New Search]