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  • Title: [Diagnostic value of parathyroid localization techniques in surgery for primary hyperparathyroidism].
    Author: Ferrer Ramírez MJ, Amorós Sebastiá LI, Cano Terol C, Caballero Calabuig E, Hernández Mijares A, López Martínez R.
    Journal: Acta Otorrinolaringol Esp; 2003 Mar; 54(3):220-4. PubMed ID: 12825345.
    Abstract:
    OBJECTIVES: To determine the accuracy of imaging techniques for localization of nodular lesions of parathyroid glands. MATERIAL AND METHODS: Seventy one patients were prospectively enrolled and underwent surgical examination for primary hyperparathyroidism. Ultrasonography (US), 201Tl/99mTc parathyroid subtraction scintigraphy and 99mTc MIBI scintigraphy were evaluated. RESULTS: The sensitivity and specificity for combined 201Tl/99mTc parathyroid subtraction scintigraphy and US for parathyroid adenomas were 72.27% and 89.22% respectively. The combination of 99mTc MIBI scintigraphy and US resulted in improved specificity (93.67%) and positive predictive value (80.39%). The accuracy of the localizing studies was lower for patients with hyperplasia. CONCLUSIONS: The combination of scintigraphy and US is the best approach for localization of nodules. In most cases, the two techniques are complementary.
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