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  • Title: Managing spasticity in spinal cord injury: safe administration of bridge boluses during intrathecal baclofen pump refills.
    Author: Elovic E, Kirshblum SC.
    Journal: J Spinal Cord Med; 2003; 26(1):2-4. PubMed ID: 12830961.
    Abstract:
    Intrathecal baclofen now plays an important role in the management of spasticity in a number of neurologic conditions including spinal cord disorders. Dosage errors can be a source of significant morbidity and the risk is greatest when the clinician is changing solution concentration. When changing concentrations, it is imperative to program the pump correctly by incorporating a bridge bolus to compensate for the residual baclofen solution in the pump and catheter. This paper reviews the appropriate methods to safely calculate the bridge bolus, with an illustrative example.
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