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  • Title: Laser and proton radiation to reduce uveal melanoma-associated exudative retinal detachments.
    Author: Char DH, Bove R, Phillips TL.
    Journal: Am J Ophthalmol; 2003 Jul; 136(1):180-2. PubMed ID: 12834689.
    Abstract:
    PURPOSE: To assess whether laser-induced hyperthermia with proton irradiation of choroidal melanoma may decrease exudative retinal detachments more rapidly. DESIGN: Case control study. METHODS: Patients treated with laser-induced hyperthermia and proton radiation; results were compared with similar patients treated with only protons. RESULTS: All 11 patients treated with combined laser and proton therapy had resorption of subretinal fluid with a mean duration of retinal detachment of 193 days compared with 263 days in the group treated with only proton therapy (P <.04). At 1 year, visual acuity was similar. CONCLUSIONS: Combined laser radiation more rapidly dissipates exudative detachments than radiation alone.
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