These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Mitochondrial signaling in apoptosis: mitochondrial daggers to the breaking heart.
    Author: Gottlieb RA.
    Journal: Basic Res Cardiol; 2003 Jul; 98(4):242-9. PubMed ID: 12835953.
    Abstract:
    Mitochondria respond to signals from the cytoplasmic environment, including energy needs, substrate and oxygen availability, ion fluxes, as well as kinase and proteolytic signals. They integrate these complex, often conflicting signals with a coordinated response, whether for growth, hibernation, or apoptosis. In this review we consider the panoply of signals that impact the mitochondria, and focus particularly on the apoptotic pathways in which the mitochondria stand at the crossroads.
    [Abstract] [Full Text] [Related] [New Search]