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  • Title: [Case report: difficulty in treating one event of Streptococcus pneumoniae meningitis].
    Author: Hizel K, Güzel O, Altunçekiç A, Gür D, Arman D.
    Journal: Mikrobiyol Bul; 2003 Jan; 37(1):65-9. PubMed ID: 12838680.
    Abstract:
    Streptococcus pneumoniae is one of the leading causes of acute bacterial meningitis and the emergence of antibiotic resistant pneumococci is an increasing problem worldwide. In this report, a 22-years-old woman was presented with pneumococcal meningitis occurring twice in a 5 months period. After the first meningitis attack, the patient had been vaccinated by 23-valent polysaccharide vaccine but the illness has relapsed. Although S. pneumoniae which was isolated from the patient has been found intermediate resistant to penicillin and susceptible to ceftriaxone by E-test, the patient could be treated only with meropenem. The case has been presented and discussed for ceftriaxone failure in spite of in-vitro susceptibility. On the other hand, this case indicated that vaccination might fail to prevent recurrence.
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