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  • Title: [Pharmacological correction of immuno-metabolic disorders with the peptide Gly-His-Lys in hepatic damage induced by tetrachloromethane].
    Author: Smakhtin MIu, Konoplia AI, Sever'ianova LA, Shveĭnov IA.
    Journal: Patol Fiziol Eksp Ter; 2003; (2):19-21. PubMed ID: 12838768.
    Abstract:
    10-day intraperitoneal administration of the tripeptie Gly-His-Lys in doses 2.5 and 150 mu/kg raises of mitotic index of hepatocytes in acute toxic damage to the liver. In the dose 1.5 mu/kg this peptie corrects both functional activity of hepatocytes and immunological responsiveness. In a dose of 150 mu/kg the peptie has a more potent immunosuppressive action and deteriorates biochemical indices of blood serum as well as dystrophic changes in the liver.
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