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  • Title: [Comparison between nuclear DNA and histologic grade of prostatic carcinoma].
    Author: Zattoni F, Prayer Galetti T, Vianello F, Bertoldin R, Panozzo M, Blandamura S, Costantin G.
    Journal: J Urol (Paris); 1992; 98(4):192-5. PubMed ID: 1284300.
    Abstract:
    DNA nuclear ploidy determined by flow cytometry was evaluated from prostate tissue in 51 patients with prostatic cancer who had undergone radical prostatectomy. DNA ploidy pattern was diploid in 46% and aneuploid in 54% of tumors. DNA ploidy was compared to histological tumor grading. 92 Aneuploidy was found in 0% of the tumors with Gleason score between 2 and 4 in 62% between 5 and 7 and in 50% between 8 and 10. Our results suggest there is no relationship between the two parameters.
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