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  • Title: Inhibition of linoleic acid hydroperoxide-induced toxicity in cultured human fibroblasts by anthocyanidins.
    Author: Kaneko T, Tahara S, Baba N.
    Journal: Biosci Biotechnol Biochem; 2003 Jun; 67(6):1391-3. PubMed ID: 12843669.
    Abstract:
    The protective effect of anthocyanidins against the toxicity induced by linoleic acid hydroperoxide (LOOH) was examined in cultured human fetal lung fibroblasts, TIG-7. Cyanidin was more effective than pelargonidin or delphinidin in inhibiting LOOH-induced cytotoxicity. The presence of a catechol moiety in the B ring is shown to be important for the protective activities against the cytotoxicity of LOOH.
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