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  • Title: Comparison of the mosquito-repelling efficacy of methyl neodecanamide (MNDA) to that of Deet.
    Author: Polefka TG, Liang LJ, Ananthakrishnan TN.
    Journal: J Cosmet Sci; 2003; 54(3):283-8. PubMed ID: 12858227.
    Abstract:
    The objective of this small pilot study was to assess the mosquito-repelling efficacy of methyl neodecanamide (MNDA) relative to N,N-diethyl-3-methylbenzamide (Deet) against Anopheles stephensi, Culex quinquefasciatus, and Aedes aegypti under controlled laboratory conditions. In this study, subjects inserted both forearms (sham- and repellent-treated) into a test chamber containing 50 female mosquitoes. The number of mosquitoes landing on or probing each forearm during the 5-minute "forced-choice" test session was recorded each hour for a total of eight hours. Effectiveness was calculated according to Abbott's formula. Experimental results indicate that topical application of 1% MNDA provided significantly better protection and a broader spectrum of repellency than application of 1% Deet against the three species of mosquitoes. These promising results support further study of MNDA as a topical mosquito repellent.
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