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  • Title: [Effect of antisperm antibodies on assisted reproduction].
    Author: Ou JP, Zhuang GL.
    Journal: Zhonghua Nan Ke Xue; 2003 Jun; 9(3):214-7. PubMed ID: 12861840.
    Abstract:
    The formation of antisperm antibodies (AsAb) results from the disruption of the blood-testis barrier by a variety of mechanisms, which leads to exposure of immunogenic sperm antigens to the immune system and initiates an immune response. AsAb can impair the fusion of sperm and egg and even the embryo development, resulting in infertility. The etiology of AsAb, effect of AsAb on assisted reproduction and treatment of AsAb in the literature are reviewed in this article.
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