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  • Title: An autoregulatory role for prostaglandins in placental hemodynamics: their possible influence on blood pressure in pregnancy.
    Author: Speroff L.
    Journal: J Reprod Med; 1975 Nov; 15(5):181-8. PubMed ID: 128632.
    Abstract:
    This review asserts that prostaglandins of the E family play a vital regulatory role in uteroplacental blood flow. This role appears to be similar to activity within other organs, especially the kidney, in a process referred to as autoregulation of blood flow. This mechanism may serve as a system for ehmodynamic homeostasis in pregnancy. Moreover, hypertension in pregnancy (toxemia) may be due to a specific or generalized abnormality in this system.
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