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  • Title: Combination therapy with caspofungin and liposomal amphotericin B for invasive aspergillosis.
    Author: Elanjikal Z, Sörensen J, Schmidt H, Dupuis W, Tintelnot K, Jautzke G, Klingebiel T, Lehrnbecher T.
    Journal: Pediatr Infect Dis J; 2003 Jul; 22(7):653-6. PubMed ID: 12867844.
    Abstract:
    Ina 24-month-old girl with acute lymphoblastic leukemia and invasive aspergillosis, only combination therapy with liposomal amphotericin B and caspofungin achieved a good response. Combination therapy could be a useful treatment option in children with invasive fungal disease, but before it can be routinely recommended, carefully controlled in vivo studies and well-designed randomized clinical trials are needed.
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