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  • Title: Pyrrolo[2,3-h]quinolinones: synthesis and photochemotherapic activity.
    Author: Barraja P, Diana P, Lauria A, Montalbano A, Almerico AM, Dattolo G, Cirrincione G, Viola G, Dall'Acqua F.
    Journal: Bioorg Med Chem Lett; 2003 Aug 18; 13(16):2809-11. PubMed ID: 12873520.
    Abstract:
    A series of derivatives of the new ring system pyrrolo[2,3-h]quinoline-2-one was synthesized and evaluated as photoreagents toward cultured human tumor cells. Remarkable phototoxycity resulted for some derivatives, especially those bearing the phenyl group at the 7-position.
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