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  • Title: [Effectiveness of eradication anti-helicobacter therapy in patients with duodenal ulcer in different drug dosage regimens].
    Author: Orziev ZM, Nurbaev FE, Rakhimova GSh.
    Journal: Klin Med (Mosk); 2003; 81(6):48-9. PubMed ID: 12875192.
    Abstract:
    46 patients having exacerbation of duodenal ulcer in the presence of Helicobacter pylori (HP) were studied for efficacy of HP eradication treatment which comprised omeprazole (40 mg/day), colloid bismuth subcitrate (480 mg/day) and metronidazole (1000 mg/day) for 2 weeks. According to the dosage regimen the patients were divided into two groups. Patients of group 1 received the drugs in fractions, of group 2--in a single daily doses. The eradication therapy in both dosage regimen was high (73 and 88%, respectively). Thus, it is proved that single daily doses of actibacterial drugs can be also used in clinical practice for conduction of eradication therapy.
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