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  • Title: Cytotoxic diterpenes from Scoparia dulcis.
    Author: Ahsan M, Islam SK, Gray AI, Stimson WH.
    Journal: J Nat Prod; 2003 Jul; 66(7):958-61. PubMed ID: 12880314.
    Abstract:
    Four new labdane-derived diterpenes, iso-dulcinol (1), 4-epi-scopadulcic acid B (2), dulcidiol (4), and scopanolal (5), together with two known diterpenes, dulcinol/scopadulciol (3) and scopadiol (6), were isolated from the aerial parts of Scoparia dulcis. The structures were determined by extensive NMR studies. The crude extracts as well as the pure diterpenes showed cytotoxicity against a panel of six human stomach cancer cell lines.
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