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  • Title: Production of teicoplanin by a mutant of Actinoplanes teicomyceticus.
    Author: Lee JC, Park HR, Park DJ, Son KH, Yoon KH, Kim YB, Kim CJ.
    Journal: Biotechnol Lett; 2003 Apr; 25(7):537-40. PubMed ID: 12882141.
    Abstract:
    Teicoplanin, a glucopeptide antibiotic, was produced by a mutant of Actinoplanes teicomyceticus at 300 mg l-1 using mannose and yeast extract as carbon and nitrogen sources in flask culture and at 500 mg l-1 in 5-1 jar fermenter. Teicoplanin production was 25-fold higher than in the parent strain.
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