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  • Title: [Stage-dependent expression of androgen binding protein mRNA in sertoli cell of rat testis].
    Author: Chen Y, Ye S, Huang Y, Zheng W.
    Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2000 Jun; 22(3):287-9. PubMed ID: 12903480.
    Abstract:
    OBJECTIVE: To investigate the variation of rat androgen binding protein (ABP) mRNA in sertoli cell of rat testis during spermatogenesis. METHODS: In situ hybridization was performed with digoxin-labeled rat ABP cDNA probe on frozen testis tissue sections from SD rats. The expression of ABP mRNA was quantified by using laser density scanning system. RESULTS: It was shown that ABP mRNA levels were low from stage I to stage VI, increased to the peak level at the stages VII-VIII, and then declined rapidly at stages IX-XI. Thereafter, ABP mRNA levels increased again at stages XII-XIV, and then decreased to the lowest level at stages I-VI. CONCLUSIONS: ABP mRNA level was stage-dependent during the spermatogenic cycle.
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