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  • Title: Bacterial genomics and vaccine design.
    Author: Sampson SL, Rengarajan J, Rubin EJ.
    Journal: Expert Rev Vaccines; 2003 Jun; 2(3):437-45. PubMed ID: 12903808.
    Abstract:
    Complete genome sequences are available for an increasing number of pathogenic bacteria. These new data are beginning to make an impact on the understanding of bacterial evolution and virulence. Thus far, however, vaccine development has had little benefit from genomics. Here we discuss how genomic sequence is being used in ways that could help identify useful bacterial antigens or create attenuated live vaccines.
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