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  • Title: [Toll-like receptor and innate immunity in phylogenesis].
    Author: Liu Y, Zhu LP, He W.
    Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2002 Aug; 24(4):433-6. PubMed ID: 12905671.
    Abstract:
    In protection against microbes, an organism recognizes the pathogen associated molecular pattern (PAMP) on microbes by pattern recognition receptor (PRR). Toll-like receptor is called innate immunity. A family of cell membrane receptor was found in recent years that can mediate innate immune responses through the activation of a series of immune-related genes. In phylogenesis, it is highly conservative. However, its functions are getting more diversified with the complication of the immune functions of organisms.
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