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  • Title: Synthesis of novel pyrimidine-2,4-diones and 2-thioxo-pyrimidine-4-ones as potential anticancer and antimicrobial agents.
    Author: Soliman R, Habib NS, Ismail K, Moustafa A, Sarg MT, Fanaki NH.
    Journal: Boll Chim Farm; 2003 May; 142(4):167-74. PubMed ID: 12918226.
    Abstract:
    Two novel series of pyrimidine derivatives have been prepared, namely; 3,6-disubstituted perhydropyrimidine-2,4-diones 8a-l as well as 3,6-disubstituted 2-thioxo-perhydropyrimidine-4-ones 9a-k. The anticancer as well antimicrobial activities of these compounds and their open-chain counterparts have been determined.
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