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  • Title: Vertebral body osteonecrosis without vertebral collapse.
    Author: Murakami H, Kawahara N, Gabata T, Nambu K, Tomita K.
    Journal: Spine (Phila Pa 1976); 2003 Aug 15; 28(16):E323-8. PubMed ID: 12923488.
    Abstract:
    STUDY DESIGN: A case of idiopathic focal vertebral body osteonecrosis without vertebral collapse is reported. OBJECTIVES: To report a rare case of focal vertebral osteonecrosis and to clarify the features of imaging studies. SUMMARY OF BACKGROUND DATA: There are no previous reports describing focal vertebral body necrosis without collapse in the literature. METHODS: A case report and literature review are presented. RESULTS: Imaging studies demonstrated: 1) sclerotic change on computed tomography scan; 2) low intensity on T1, high intensity on T2 with clear margin, and no gadolinium enhancement on magnetic resonance imaging; and 3) no uptake on bone scan. Histologic examination revealed empty lacunas, fatty necrosis with vacuolar degeneration, and cell debris compatible with bone marrow necrosis. CONCLUSION: Vertebral body osteonecrosis must be considered a possible diagnosis of patients presenting with low intensity on T1, high intensity on T2 with clear margin, and no gadolinium enhancement on magnetic resonance imaging.
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