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  • Title: [The effect of 4-aminopyridine of the synaptic activity in the last abdominal ganglion of the cockroach (Periplaneta americana)].
    Author: Hue B, Pelhate M, Callec JJ, Chanelet J.
    Journal: C R Seances Soc Biol Fil; 1975; 169(4):876-83. PubMed ID: 129257.
    Abstract:
    Synaptic action of 4-aminopyridine (4-AP) has been studied in the sixth abdominal ganglion of the cockroach. Our results show that 4-AP has a strong excitatory effect on the ganglion and its seems that it depolarizes as well the pre and postsynaptic membranes. The threshold concentration is about 10(-5) M.
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